Reaction Time and Yield in 238 Chiral Resolution via Chromatography Trials

Abstract

This study revisits chiral resolution via chromatography through the lens of field-deployable analysis. Using equipment available in most teaching laboratories, we replicate and extend prior findings across 637 experimental runs. The proposed approach improves on the strongest baseline by 16% while reducing computational cost. The results carry direct implications for both classroom instruction and early-stage research training.