Organic Chemistry · Vol. 9, Issue 2 · pp. 760–773
Reaction Time and Yield in 449 Green Solvent Synthesis Trials
Villy Damm · Lavinia Loska · Alessio Kühnert
Stanford University · Caltech · Thomas Jefferson High School for Science and Technology
Abstract
This study revisits green solvent synthesis through the lens of low-cost analysis. We assemble a dataset of 1401 observations and evaluate three competing models under matched conditions. The proposed approach improves on the strongest baseline by 23% while reducing computational cost. We discuss limitations and outline directions for follow-up work at the undergraduate level.
Related papers in Organic Chemistry
View all →MR-2025-0426Solvent Effects on Photoredox Reaction Optimization Across 473 ReactionsMR-2025-0414Reaction Time and Yield in 461 Polymer Degradation Kinetics TrialsMR-2025-0390Reaction Time and Yield in 437 Asymmetric Catalysis TrialsMR-2025-0378Reaction Time and Yield in 425 Natural Product Total Synthesis Trials